NovoLog® Mix 70/30 Frequently Asked Questions

Whether you've been taking NovoLog® Mix 70/30 (insulin aspart protamine and insulin aspart injectable suspension) 100 U/mL for a while, or you're just looking for information, you probably have questions. You can browse our frequently asked questions section below to find answers to those questions. If you don't find answers to your questions here, call the Novo Nordisk Customer Care Center at 1-800-727-6500, or consult with your health care professional.

How is NovoLog® Mix 70/30 different from other types of insulin?

NovoLog® Mix 70/30 is different because it is a single insulin that works in 2 ways. When taken twice a day as directed by your doctor, it works fast to cover blood sugar surges at meals, and also has an extended release that can last up to 24 hours.

Top ››

How is NovoLog® Mix 70/30 different from human premix insulin?

NovoLog® Mix 70/30, like regular human insulin, is man-made. However, NovoLog® Mix 70/30 is an analog insulin, a more recent type of insulin than human insulin. For more information, read A Different Premix Insulin Option.

Top ››

Can I take NovoLog® Mix 70/30 with other medicines?

NovoLog® Mix 70/30 can be taken along with non-insulin diabetes medicine. Before you use NovoLog® Mix 70/30, tell your health care provider about all medicines you take, including prescriptions and non-prescription medicines, vitamins, and herbal supplements. NovoLog® Mix 70/30 may affect the way other medicines work, and other medicines may affect how NovoLog® Mix 70/30 works. Your NovoLog® Mix 70/30 dose may change if you take other medicines.

Top ››

How should I take NovoLog® Mix 70/30?

Take your NovoLog® Mix 70/30 exactly as your health care provider tells you. Your health care provider will tell you how much NovoLog® Mix 70/30 to take and when to take it. Do not make any changes to your dose or type of insulin unless your health care provider tells you to.

NovoLog® Mix 70/30 starts acting fast. If you have type 2 diabetes, inject NovoLog® Mix 70/30 within 15 minutes before or after starting your meal. If you have type 1 diabetes, inject it within 15 minutes before you start a meal. Do not inject NovoLog® Mix 70/30 if you are not planning to eat within 15 minutes.

Read the Instructions For Use that come with your NovoLog® Mix 70/30. Talk to your health care provider if you have any questions. Your health care provider should show you how to inject NovoLog® Mix 70/30 before you start using it.

Top ››

What can I do if I have trouble remembering to take NovoLog® Mix 70/30?

To help you remember to take your NovoLog® Mix 70/30 dose, you may want to set an alarm on your cell phone to go off at breakfast, lunch, or dinnertime. Or you can leave notes on your refrigerator. For automatic reminders, sign up to get text alerts sent to your phone to let you know when it’s time to take your insulin. Before long, you may get used to taking NovoLog® Mix 70/30 with meals and it will become an automatic part of your daily routine—like brushing your teeth.

Top ››

What do I need to consider about my diabetes care plan?

Including more physical activity to your routine and closely following the meal plan your diabetes care team created for you are both excellent ways to help manage your blood sugar. You may also need your NovoLog® Mix 70/30 dose to be adjusted. Check your blood sugar readings regularly. And share those results with your health care provider. Then you and your health care provider can determine how best to tailor your insulin therapy to your needs.

Top ››

What type of needles can I use with NovoLog® Mix 70/30 FlexPen®?

NovoLog® Mix 70/30 FlexPen® can be used with NovoTwist®, NovoFine®, and NovoFine® Plus needles. NovoFine® Plus 32G Tip needles are the shortest and thinnest needles available from Novo Nordisk. NovoFine® Plus is designed to make injections more comfortable for you.

Needles are sold separately and may require a prescription in some states.

Top ››

Does NovoLog® Mix 70/30 FlexPen® need to be refrigerated?

Keep unopened NovoLog® Mix 70/30 FlexPen® or vials in the refrigerator between 36°F and 46°F. Do not freeze. Once opened, do not refrigerate NovoLog® Mix 70/30 FlexPen®; keep it at room temperature (below 86°F) for up to 14 days. NovoLog® Mix 70/30 vials, once in use, can be kept refrigerated or at room temperature (below 86°F) or for up to 28 days. Throw away an in use opened vial after 28 days of use, and in use NovoLog® Mix 70/30 FlexPen® after 14 days, even if there is insulin left in it.

Top ››

Can taking 1 insulin with 2 actions help give me the control I need?

NovoLog® Mix 70/30 is 1 insulin that works in 2 ways to help control your blood sugar. It has both fast action to cover your mealtime blood sugar and extended action that can last up to 24 hours to cover your blood sugar between meals. NovoLog® Mix 70/30 is typically taken twice a day.

Top ››

When do I take NovoLog® Mix 70/30?

Because NovoLog® Mix 70/30 works fast, you can take it within 15 minutes before OR after starting a meal if you have type 2 diabetes. And it comes in FlexPen®. FlexPen® fits in your purse or pocket. So you can take it almost anywhere you want, when you want.

Top ››

What are the delivery options for NovoLog® Mix 70/30?

NovoLog® Mix 70/30 comes in FlexPen® and vials. You and your doctor will decide which insulin delivery system is right for you.

Top ››

How can I benefit from NovoLog® Mix 70/30 if I'm just starting out with insulin?

If you've never taken insulin before, either because you've just been diagnosed with diabetes or you've been taking diabetes pills alone, NovoLog® Mix 70/30 can help you control your blood sugar. It's 1 insulin with 2 actions. So you don't have to carry 2 types of insulin. And it comes in NovoLog® Mix 70/30 FlexPen®, which you can take almost anywhere.a Ask your doctor about NovoLog® Mix 70/30 today.

aOnce in use, NovoLog® Mix 70/30 FlexPen® must be kept at room temperature (below 86°F) for up to 14 days. Throw away an unrefrigerated, disposable NovoLog® Mix 70/30 FlexPen® after 14 days, even if it still contains insulin. Throw away unrefrigerated vials after 28 days, even if they still contain insulin.

Top ››

I'm currently taking a human premix insulin. Why should I consider NovoLog® Mix 70/30?

NovoLog® Mix 70/30 is typically taken twice a day and may help meet your needs at mealtime and for up to 24 hours. In people with type 2 diabetes, NovoLog® Mix 70/30 can be taken within 15 minutes before OR after starting a meal, unlike human premix insulin, which requires dosing at least 30 minutes before meals. If you're not reaching your blood sugar goals, talk to your doctor about NovoLog® Mix 70/30.

Low blood sugar (hypoglycemia) is the most common side effect of insulin, including NovoLog® Mix 70/30. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit, or call 1-800-FDA-1088.

Top ››

How do I pay for NovoLog® Mix 70/30?

NovoLog® Mix 70/30 is covered on most health insurance and Medicare plans. Please check with your health plan for details.

Top ››

What if I have more questions?

For more information, please call one of our specially trained Customer Care Representatives at 1-800-727-6500, or ask your doctor.

Top ››

NovoLog® Mix 70/30 FlexPen®

Learn more about our discreet, prefilled, dial-a-dose pen.

Learn More


Your diabetes, your way. Learn about the 4 basics of diabetes care on Cornerstones4Care®.

Sign Up